What is dupilumab and how does it work?

Dupilumab is a biologic medicine that is designed to treat eczema. It works by reducing inflammation. It works on chemical messengers (known as a ‘cytokines’) in the body called ‘interleukin-4’ (IL-4) and ‘interleukin-13’ (IL-13). These 2 chemical messengers have a major role in causing inflammation and atopic eczema and thus dupilumab can block the action of these 2 messengers.

Why should I use dupilumab?

Dupilumab is effective for patients with moderate to severe atopic eczema. It may reduce the use of topical or oral steroid which could be a major concern to some patients.

Is dupilumab safe for children and adolescents?

Dupilumab is safe for children aged 6 to 11 years with severe atopic dermatitis, and adolescents aged 12 to 17 years with moderate-to-severe atopic dermatitis.

How do I take dupilumab?

Dupilumab is given as an injection under your skin (subcutaneously).

How often should I take dupilumab?

Dupilumab should be injected every 2 weeks.

Can I take other medicines at the same time as dupilumab?

Most medicines are safe to take with dupilumab. However, it is important that your doctors are aware that you are taking it.